QC/QA analyzer system in powder, tablet and capsule production

Process NIR Analyzers

Powder, tablet and capsule production

 

AppliTek offers non-destructive and non-contact analytical near infrared (NIR) technology for multi -component analysis of pharmaceutical products in all stages of the production process, from raw material ID to tablet inspection. Physical and chemical properties in powders, tablets, capsules and even liquids are measured on-line and at high scanning rates.

The NIR analyzers are implemented either directly in-line or through fiber optics. The best possible solution will be choosen according to your application or site requirements. 21 CFR Part 11 Compliant  software is part of the supply for pharmaceutical applications.

 

Applications

  • Manufacture of excipients, actives
  • Manufacture of capsules
  • Incoming raw materials
  • Dispensary (active, exc ipients)
  • Blending, granulation
  • Transdermal patches
  • Inspection of product (before/after packaging)
  • Solvent recovery
  • Drying (FBD, Spray, etc.)
  • Blend/Dryer Ending Point Monitor

 

Parameters

Theoretically, distinct fingerprints can be linked to any chemical or physical component present in the sampled object and modeled for prediction. However, process changes, recipe changes or impurities may require additional modeling.

Please contact us for your parameter(s).

 

Product list for powder, tablet and capsule production:

 

In situ NIR spectrometer

Solid-state compact NIR analyzer designed for non-invasive measurements on powders, pellets, liquids… Ideal for implementing in the actual process by means of direct reflectance mode or through a window...

Options / Extra  Several sampling spool pieces for insertion in the process line, stainless steel 303, sanitary flanges, sapphire window

On-line NIR spectrometer

Field proven solution for measurements of chemical and physical properties of up to 8 sample streams within seconds. A wide variety of fibers, probes, flow cells can be used in any combination and in process areas with different safety area classifications...

 

For the detailed specifications of these spectrometers, please check the following section:

» Go to  Analyzers / NIR process analyzers

Additionally, a handheld NIR analyzer for manual measurements is also available:

» Go to  Analyzers / Lab - Portable

 

General features

Diffuse reflectance mode

High signal to noise ratio

NEMA 4x encloure / NEMA 12 for in situ system

Dual beams, pre-aligned lamp assembly, InGaAs detectors, temperature regulated

Embedded computer, ethernet interface

Snap!32 Analytical Software - Appropriate chemometrics software

 

 

 

 

 

Images